Cas9/guide RNA (gRNA)‐based gene drive systems are expected to play a transformative role in malaria elimination efforts., whether through population modification, in which the drive system contains parasite‐refractory genes, or population suppression, in which the drive system induces a severe fitness load resulting in population decline or extinction. DNA sequence polymorphisms representing alternate alleles at gRNA target sites may confer a drive‐resistant phenotype in individuals carrying them. Modeling predicts that, for observed levels of SGV at potential target sites and observed (...) rates of de novo DRA formation, population modification strategies are uniquely resilient to DRAs. We conclude that gene drives can succeed when fitness costs incurred by drive‐carrying mosquitoes are low enough to prevent strong positive selection for DRAs produced de novo or as part of the SGV and that population modification strategies are less prone to failure due to drive resistance. (shrink)

Health‐related data uses and data sharing have been in the spotlight for a while. Since the beginning of the big data era, massive data mining and its inherent possibilities have only increased the debate about what the limits are. Data governance is a relevant aspect addressed in ethics guidelines. In this context, the European project BRIDGE Health (BRidging Information and Data Generation for Evidence‐based Health policy and research) strove to achieve a comprehensive, integrated and sustainable EU health‐information system. One of (...) the aims of the project was to evaluate the requirements to construct a data‐linkage infrastructure for the secure management of health information. In a blueprint provided for this infrastructure, the topics ethics and the intimately related governance occupied a whole section, where the recent ethics guidelines by the Council for International Organizations of Medical Sciences (CIOMS) and the World Medical Association (WMA) were referenced. We explore what has changed in the latest versions of the ethics documents adopted by CIOMS and WMA regarding the management of health data and human tissues, the appropriateness of their application in new forms of research and infrastructures as the proposed in the BRIDGE Health project, and whether society should be so concerned about this topic, in the digital era of social exchange. (shrink)

Membership in voluntary organizations is associated with individual and social benefits. Due to the negative consequences of the global pandemic on older people, and the governmental challenges posed by population aging, voluntary membership is of great importance to society. To effectively promote volunteering among older people, it is necessary to understand the determinants of voluntary membership. This study analyses the influence of individual values—secular/traditional and survival/self-expression–on voluntary membership among European adults. Specifically, it examines which values orient two age groups, as (...) well as men and women toward a certain type of association. The sample of 31,985 comprises 60% of adults aged 50–64 and 40% aged 65–79; of which 56% are women and 44% men. The empirical estimation considers different levels of data aggregation: individual, national and welfare system, therefore multilevel analysis is used as an analytical strategy. Individual-level variables from the Integrated Values Survey and national-level variables from the World Bank and Eurostat are used. The results indicate that traditional and self-expression values promote membership in voluntary organizations in general more than secular and survival values. However, there are differences according to the type of organization. Furthermore, values are found to moderate the effect of age and gender on voluntary membership. (shrink)

Este artículo realiza un análisis léxico-semántico de la terminología irreligiosa en la literatura griega. Se ha seleccionado un término clave y un autor relevante a fin de ilustrar la importancia del fenómeno irreligioso en la sociedad de Época Clásica. El adjetivo ὅσιος describe el respeto religioso en acciones y actitudes hacia las divinidades y también hacia otros seres humanos. Sófocles usa la forma privativa ἀνόσιος en contextos donde falta ese respeto religioso, con consecuencias negativas para la polis.

The percentage of female entrepreneurs is far below the level of males, although it has increased over the past several years. Based on the theory of planned behavior, the purpose of this article is to specify a model in which the relationship among entrepreneurial potential, gender and entrepreneurial intention are explored, by analyzing how perceived behavioral control (PBC) and perceived entrepreneurial skills, as exogenous variables, affect expression of intention for business, and how these are mediated by their entrepreneurial motivations and (...) risk taking propensity. Control variables where also included in this model, such as necessity-driven motives for business, in order to observe whether these are an influential factor. An implementation of Structural Equation Modeling (SEM) was used to analyze data collected from 677 students. Variables within the model were compared by gender using t-Test, and all multivariate analysis were done by each one separately as well in order to better gauge their perceptions. Results showed that mean differences between males and females are not abundant, and come only from intentions, PBC and subjective norm, which are higher in males; and motives for business higher in females. Multivariate analysis shows gender differences at the mediation level and that necessity-driven motives are an influencing factor, more so in males, and it hampers the significance of subjective norm. Finally, the theoretical and practical implications of the results within the framework of entrepreneurship in Spain and future alternatives to improve the entrepreneurial potential are discussed. (shrink)

The formalization of abductive reasoning has received increasing attention from logicians. However, few work is found beyond abduction in propositional logic, given that in a first order formalism, the undecidability problem naturally appears, and therefore an abductive problem cannot even be appropriately formulated. Still, many applications in artificial intelligence allow finite domains to work with, and this gives an opportunity to apply abduction in first order logic with restricted domains. In this paper, we present an approach to abductive reasoning in (...) C-structures, first order structures with a finite domain in which each of its elements has a corresponding constant representing its interpretation. By using semantic tableaux with bounded depth, that is, C-tableaux (a modification of N-tableaux, introduced by the authors in previous papers) and δ-resolution calculus, we build an effective procedure for the searching of minimal abductive solutions within the proposed semantics. (shrink)

Since there are so few controls over detecting and preventing faculty misconduct, one of the most common ways in which it is discovered is through student reports. Given the importance of student reports in bringing to light faculty’s ethical lapses, this paper seeks to understand what factors influence students’ likelihood to report faculty misconduct. We develop an empirical model that integrates the decision process of the Prosocial Organizational Behavior Model with insights from the emotional perspective on whistleblowing. Specifically, we use (...) an experimental survey to examine how students’ perceived unfairness of the faculty misconduct, feelings of anger, and the students’ self-interest in the situation in conjunction with situational “cues for inaction” lead to the intention to blow the whistle. Overall, the results from our structural model partially support our theoretical model. Interestingly, these findings demonstrate that, in the case of faculty member misconduct, anger and perceptions of unfairness play a greater role than the more rational cost-benefit process of the POB model. These results could aid in development of ethics education for students and could also inform the development of university policies that encourage students to come forward when faced with faculty misconduct. (shrink)

Running marathons is an increasingly popular activity with an ever-increasing number of events and participants. Many participants declare that they pursue a variety of goals by running, namely, the maintenance of good health, the development of strength and improvement of fitness, the management of emotions, and the achievement of resilience and psychological wellbeing. The research has examined marathon running, like many other sports, and has studied various factors that reduce athletic performance, such as the experience of anxiety, and that enhance (...) such performance, such as an increase in general wellbeing. This article reports the results of a study on the experience of competitive anxiety among 238 male marathon runners who participated in Seville’s 26th Marathon race on February 23, 2020, and investigates the relationship between anxiety and key dimensions of wellbeing as measured by the Spanish-adapted 20-item PWB Scale. We hypothesized that participating athletes who rated high on the dimensions of PWB would experience lower levels of competitive anxiety with respect to this race. We also proposed that PWB would function as a mediating factor with respect to the experience of anxiety. The results show, as hypothesized, that marathon running enhances wellbeing and reduces anxiety. The data showed significant negative correlations between four of five wellbeing dimensions and the three types of anxiety measured, namely, somatic anxiety, worry, and concentration-impairing anxiety. Other findings supported our hypothesis that wellbeing, as measured, functions as a mediating factor for the moderation of competitive anxiety. Generalization of these findings is limited by the fact that the low number of female participants recruited did not permit valid statistical analyses in this respect. It is known that both anxiety and wellbeing are subjects to variation by gender. The future inclusion of male and female subjects in equivalent studies will undoubtedly add valuable information concerning the dynamics of anxiety and wellbeing. The implications of these findings and the limitations of the study will be discussed. (shrink)

La relación que Ricoeur establece entre lo bueno, lo justo y la convicción permite postular un círculo hermenéutico —semejante al que Heidegger propone en su ontología fundamental, y que Gadamer complementa en Verdad y método— en la filosofía práctica, conformado por tres momentos: lo bueno, lo justo y su aplicación al contexto que lo demanda. Con su “pequeña ética”, mediada por esta reformulación, Ricoeur pretende terciar en la discusión entre la ética de la argumentación de Habermas y el comunitarismo e (...) historicismo de C. Taylor, A. MacIntyre y H.-G. Gadamer. (shrink)

RESUMEN Desde 1980, C. D. Frith investiga la esquizofrenia, y explica sus síntomas centrales como las alucinaciones, con miras a aclarar cuál es el déficit originario de este trastorno mental. Frith propone una hipótesis centrada en el concepto de conciencia, que ha elaborado como parte del desarrollo científico contemporáneo. En primer lugar, como parte de la aplicación de modelos neurocognitivos de control motor, según los cuales el déficit se atribuye al concepto de copia eferente y su función. En segundo lugar, (...) la actualiza y complementa con evidencia de imagen cerebral de la atenuación de la actividad cortical parietal, como efecto derivado de la copia eferente. En tercer lugar, adiciona el concepto de sentido de agencia, y el componente de cognición social, intentando integrar la experiencia del paciente y la relevancia del ámbito intersubjetivo a su propuesta. Este artículo hace una revisión crítica de la hipótesis de Frith y se divide en cuatro partes: primero, se presenta una síntesis de la evolución de la hipótesis; segundo, se sintetiza su argumentación; tercero, se presentan los principales puntos críticos y, por último, se derivan unas conclusiones generales. ABSTRACT Since 1980, C. D. Frith has been working on schizophrenia, and explaining central symptoms such as hallucinations, in an attempt to clarify the basic deficits of this mental disorder. Frith has put forth a hypothesis based on the concept of consciousness, and has been adjusting it alongside contemporary scientific developments. In first place, it begins with the use of neurocognitive models of motor control, according to which the deficit is attributable to the concept of efferent copy and its function. In second place, he updated the model by including neuroimaging evidence of attenuation in parietal activity, as a consequence of the efferent copy. In third place, he added the concept of sense of agency, and the social cognition component, trying to integrate to his proposal the patient's experience and the relevance of the inter-subjective aspect. The current paper, which critically reviews Frith's hypothesis, it's divided in four parts: First, the hypothesis' evolution is synthesized; second, the main arguments are summarized; third, the main critical points are presented; and, finally, some general conclusions are drawn. (shrink)

Este artigo apresenta um exame da crítica proposta por Morton White em seu artigo “Valor e obrigação em Dewey e Lewis”, em particular, a aquela voltada para o conceito de normatividade e valoração de C.I. Lewis. A crítica afirma que Lewis, ao oferecer um caráter normativo dos juízos éticos, malogra ao articular consistentemente a sua concepção ética com a sua teoria do conhecimento. Isso leva White a concluir que o pragmatista não possui uma solução para o problema fundamental da ética. (...) Argumentarei que tal conclusão é equivocada. O núcleo da minha argumentação repousa na tese de que a crítica de White se origina de uma interpretação incorreta do pragmatismo conceitualista de Lewis, falhando em reconhecer que o apriorismo pragmático é a chave para o entendimento adequado de teoria do conhecimento e para uma explicação da conexão e articulação entre valoração e normatividade no interior da abordagem de Lewis. Nesta linha, mostrarei que, muito pelo contrário, a epistemologia de Lewis destaca os desenvolvimentos éticos e normativos, revelando uma teoria naturalística de valoração que é a base na qual a normatividade emerge pragmaticamente. Sustentarei, também, que essa perspectiva oferece uma concepção profícua de valores e normas que não têm sido suficientemente exploradas; algo que confronta o ceticismo ético, podendo levar em conta o status cognitivo de valores e normas, e que recupera o caráter racional da valoração não apenas para a ética, mas, também, para o conhecimento e a ciência. (shrink)

Blanco, Carlos. Historia de la neurociencia: el conocimiento del cerebro y la mente desde una perspectiva inter-disciplinar. Madrid: Biblioteca Nueva, 2014. 296 pp.

El texto propone una nueva interpretación para la descripción que realiza Tácito ( _Ann_. 2.60-61) del viaje por Egipto de Germánico (19 d. C.). El autor establece paralelos de este texto con las _Historias_ de Heródoto para definir una intención teórica en el mismo. Tácito utiliza este episodio egipcio para reflexionar sobre los métodos y las posibilidades de alcanzar certezas por medio del discurso histórico.

El siguiente trabajo pretende explicar la teoría de la individuación de Gilbert Simondona partir de (a) la teoría de la individuación como crítica a la filosofía tradicional,(b) las nociones de información y relación, y (c) la ética del devenir. En la primeraparte, se comparan las críticas de Heidegger al modelo de verdad como adecuacióncon las bases de la ontología de Simondon. En el siguiente apartado, se interpretael concepto de individuación a partir de conceptos como relación e información.La última parte compara (...) la ética del devenir que defiende Simondon con la ética deLevinas. (shrink)

A la luz de la propuesta arendtiana de espacio público, en este artículo se analiza uno de los conceptos que más interés está despertando en el contexto de la llamada filosofía política continental: lo común. Desde una revisión comparada con la obra de C. Laval y P. Dardot enfrento los siguientes interrogantes: ¿Qué perspectivas abre la obra arendtiana en la actual reflexión sobre lo común como principio político articulador? ¿Qué nuevas cuestiones suscita la idea de espacio público como comunidad política (...) de Arendt al confrontarla con la propuesta de lo común? (shrink)

Ce chapitre aborde l’histoire des avocats au Mexique depuis la microanalyse, c’est-à-dire pour en proposer une histoire globale à partir d’une échelle réduite et pendant la période de consolidation de ce qui était considéré comme une administration judiciaire moderne et professionnalisée, à la veille de la Révolution. Sont abordées les questions de leurs origines sociales, leur formation, la concurrence des conseillers juridiques informels, le coût de leurs services, la qualité de leurs relations, parfois houleuses, avec leurs clients. En dernière partie (...) est traité un aspect très particulier de leur histoire : le fait qu’ils constituaient le vivier d’où étaient nommés juges et notaires, violentant ainsi la constitution libérale. Pour cela, ont été mobilisées des sources judiciaires, des lettres adressées ou rédigées par l’Exécutif de l’État de Tlaxcala ainsi que quelques sources notariales. (shrink)

Résumé : Les domaines de la philosophie et de la théorie politique ont connu un certain nombre de changements au cours des quarante dernières années. L'un attire notre attention tout particulièrement ; le basculement d'un point de vue national, cristallisé par le contrat social rawlsien, vers un point de vue non-national. En effet, plusieurs penseurs abordent un ensemble de phénomènes considérés comme nouveaux, tels que les traités de libre commerce et l'économie globale, les entreprises et les institutions supra et transnationales, (...) l'immigration et les contrôles frontaliers etc. Ces changements sont intéressants puisqu'ils obéissent, principalement, à une évolution majeure du terrain politique et social que l'on appelle mondialisation. Les théoriciens travaillant dans le domaine de la justice globale semblent s'adresser à deux questions différentes mais reliées. La première concerne la justice globale : dans quelle mesure et pourquoi l'ordre mondial est-il juste ou injuste ? Qu'est-ce qu'un ordre global juste ? La deuxième est dans un sens corollaire à la première, et concerne la responsabilité : qui devrait être blâmé ou digne d'éloge pour l'ordre mondial ? Est-ce que les citoyens sont responsables de l'ordre mondial ? Qui devrait redresser ses éventuelles conséquences injustes ? Face à l'économie mondialisée et aux institutions politiques et économiques internationales et trans-nationales, cette interrogation devient légitime et nécessaire : suis-je responsable à l'égard des travailleurs des sweat shop lorsque j'achète des habits à Auchan ou bien à l'égard des caféiculteurs très mal payés lorsque je prends un capuccino dans un café Starbucks ? Est-ce que les citoyens sont responsables des traités de libre commerce que leurs gouvernements signent ? Ces questions sur la responsabilité des individus dans le contexte de la mondialisation seront l'enjeu de ce travail de recherche. Nous interrogerons plus exactement la responsabilité d'un agent lorsqu'il fait partie d'un chaîne causale complexe, lorsqu'il participe d'une injustice structurelle. Ainsi, il ne s'agit pas seulement d'une chaîne causale, mais de connexions qui sont l'issue d'un changement des modes de productions, de consommation et de la concurrence dans un marché mondialisé. Plus important encore, il ne s'agit pas simplement de la responsabilité individuelle mais plutôt de la responsabilité individuelle en tant que citoyen, et donc d'une responsabilité politique. Elle peut certes être individuelle, mais nous devons tenir compte du fait qu'elle doit être pensée en tant que responsabilité politique, et pas uniquement morale, puisque l'individu et ses actions sont déterminés par des communautés politiques dans lesquelles il participe, ou dans lesquelles il est représenté. Ainsi, la mondialisation nous invite à repenser la responsabilité individuelle pour pouvoir rendre compte des intuitions morales et politiques qui guident une bonne partie du champ de la justice globale. Pour cela, nous verrons dans un premier temps la manière dont les théories de la justice globale essaient de répondre à ce défit. Grâce à cela nous dégagerons l'hypothèse qui nous guidera, l'idée que dans la mondialisation, un agent peut être responsable, avec d'autres, des raisons pour lesquelles il n'est pas considéré comme responsable. C'est-à-dire qu'il sera méta-responsable. Dans un second temps, nous essaierons de déterminer un model de responsabilité individuelle, et de comprendre comment la responsabilité est attribuée. Ensuite, nous essaierons de formuler une manière de concevoir la responsabilité politique. Grâce à ces deux éléments, la responsabilité individuelle et la responsabilité politique, nous pourrons parvenir à formuler une conception de la méta-responsabilité comme forme de penser l'agentivité traversée par la mondialisation. (shrink)

En este trabajo se define formamente el concepto de representacion en química utilizando homomorfismos desde estructuras algebraicas, que llamamos sistemas de tipo C, en otras estructuras especiales de símbolos muy relacionados con los que son habituales en la qímica experimental. Para la definicion de los sistemas de tipo C se ha seleccionado un conjunto minimo de relaciones y funciones, que son necesarias para expresar proposiciones significativas en química. Tambien se define un lenguaje formal de primer orden adecuado a los sistemas (...) de tipo C, que llamamos L. EI resultado principal que se demuestra es que toda representación que verifica las mismas sentencias de L que un sistema de tipo C, es necesariamente isomorfo a él. Se concluye por lo tanto que puede existir un problema linguístico subyacente en la aplicacion que de la mecaníca cuántica se hace en la química teórica.The concept of representation in chemistry bas been formallv defined by means of homomorphisms from algebraical structures, which we call type-C systems, to some special sets of symbols which can be related to the symbols ordinarily used in experimental chemistry. A minimum number of relations and functions, which would suffice to express significant propositions in chemistry, have been chosen to define type-C systems. A first order formal language L adequate to type-C systems has been defined. It has been shown that each representation that verifies the same sentences of L as a type-C system is necessarily isomorphic to it. It is concluded that a systematic study of the representation problem in chemistry is in order because a deep language problem underlies the application of quantum mechanies to chemical problems. (shrink)

Study of the arising and evolution of printings, newspapers and magazines in Cuba. The probleins are exposed that prevented the arrival of new printings in The Havana as well as in the remaining populations of the Censorship Board. It is concluded that th'c econoniic espansion recorded in the late XVIII century, was caused by, the sugar factory bloom in connection with the war and political accounts of the metropoli, along the two earliest XIX's decads. All of this provoked the take (...) off and evolution of the printing culture in Cuba. In spite of the former, sonie ciclicity is noteworthy, as logical result of an eventually disfavourable socio-political context. (shrink)

This article offers a review of the chapter dedicated by Strawson to the concept of a person in Individuals. Characteristics given to the concept of person by Strawson are criticized by Bernard Williams. What I set out to show is that this criticism can be answered by reviewing: a) how Strawson understands that the concept of a person is primitive, b) what are the implications of affirming the primitiveness of such concept, and, mainly c) what this philosopher understands by referring.

Pinhas Sadeh was considered as an unorthodox writer as regards his environment, the “State Culture” in Israel. In the first part of this paper I present the biography of the author and his most representative work, Life as a parable, published in 1958, as well as his romantic and frankist roots and his leaning towards Christianity according to the Gospel. In the second part a mythical analysis of this work is made according to the inner journey of hero, through which (...) the main character is looking for his life meaning. In this second part I present my methodology, based on works of the Eranos Society (Mircea Eliade, C.G. Jung, Gilbert Durand). Afterwards, I analyse the mithems that I have found in Life as a parable. Finally, I make a mythical comparison between this novel and Siddharta, of Hermann Hesse. (shrink)

En la coyuntura histórica, turbulenta y apasionante a la vez del Humanismo Renacentista, caracterizada por la vuelta a la Antigüedad clásica y por la renovación de principios en todas las manifestaciones culturales, resultan afectadas, desde sus mismos cimientos, la filosofía y la religión. Esta crisis escolástica incide de tal manera en la conciencia de los individuos y de los pueblos, que exige sin demora una solución, aun cuando sea provisional, que haga posible a los hombres el simple fenómeno de seguir (...) viviendo como tales. Nada tiene, pues, de extraño que entre las ruinas de la Moral tomista surjan impulsos moralizadores, como el de Justus Lipsius (1547-1606), queriendo renovar las doctrinas estoicas de Epicteto (ca. 50 a. de C.-125/138) y Séneca (ca. 4-65) y el de Pierre Gassendi (1592-1655), empeñado en cristianizar a Epicuro. Para algunos, a esto se reduce, más o menos, la Etica del Renacimiento. Otros opinan que la primera Ética de la filosofía moderna hay que buscarla entre los grandes filósofos, que sin pertenecer cronológicamente al Renacimiento, son consecuencia madura de él. Se refieren a Descartes (1596-1650), Spinoza (1632-1677) y Kant (1724-1804). Pero en opinión de significativos autores, no hay que remontarse hasta Kant para hallar la auténtica Ética del Renacimiento. Juan Luis Vives publicaba en 1524 un pequeño librito titulado Introductio ad Sapientiam [Introducción a la Sabiduría], que por su estructura ideológica interna y por su ascendencia senequista y cristiana ocupa un lugar preferente entre las Éticas modernas, y por su contenido y cronología puede ser considerada como la Ética del Renacimiento, al menos del Renacimiento español. (shrink)

Gràcies a l’aposta tecnològica de les societats actuals i també a la globalització que comporta, el moviment transhumanista, visiblement heterogeni, està començant a ser conegut a tot el globus terraqüi i a adquirir una enorme volada. Això no obstant, malgrat que la materialització de les fites transhumanistes només sigui possible en les societats postmodernes, l’origen del transhumanisme bé pot anar més enllà del que anomenem societat contemporània. En aquest article s’explora l’origen del transhumanisme partint de les tres hipòtesis següents: a) (...) el transhumanisme com un fenomen típicament postmodern; b) el transhumanisme com a herència de la tradició renaixentista secular; c) el transhumanisme com a tret identificatiu de la naturalesa humana. (shrink)

El presente ensayo pretende, en su esencia, mostrar cómo el poder de la palabra es capaz de sanar dentro del contexto ritual de los cultos desde la Antigüedad Clásica, circa IV o III milenio a. C. Igualmente, se observa la aplicación de las más modernas teorías psiquiátricas con respecto a esta problemática.

Nunca es fácil emitir un juicio de valor sobre el impacto de un autor en la tradición. Es verdad que hay nombres cuya influencia a lo largo de los tiempos es incuestionable, pero otros van y vuelven cíclicamente con variaciones en las valoraciones sobre la calidad y proyección de su obra o en su papel como hombres de acción. Jenofonte de Atenas (_ca. _431-354 a.C.) es uno de esos casos, muy apreciado hasta el siglo XIX, olvidado después hasta su recuperación (...) como filósofo político de primera línea por Leo Strauss, o como historiador imprescindible para los especialistas en Esparta, la antigua Persia aqueménida o la historia de Grecia de finales del s. V y primera mitad del IV a.C. Los filósofos lo han visto casi siempre como un pensador menor, comparado con su maestro Sócrates, con su contemporáneo Platón o con el más joven Aristóteles. (shrink)

En este artículo se resaltan las semejanzas entre el teatro griego de los siglos V y IV A.C, y los aspectos dramáticos de la Apología de Sócrates y el Banquete de Platón, argumentando a favor del carácter filosófico de aspectos como la puesta en escena y el manejo de los personajes. Parahacerlo se replantea la relación entre la obra de Platón y la de los poetas, cambiando el foco de atención de su famosa censura a las representaciones teatrales, para iluminar (...) su empleo de mecanismos dramatúrgicos articulados con planteamientos éticos y políticos. Se concluye que Platón utiliza recursos del teatro griego, pero los extrapola y los transforma creando un nuevo tipo de drama. (shrink)

Desde la teología y la filosofía podemos comprender el concepto de belleza en el deporte ligado a la dignidad humana. Para ello, en este artículo: a) analizamos desde la antropología del cristianismo el lugar del cuerpo y el valor del deporte en la vida del ser humano; b) abordamos la estética intentando comprender la belleza ligada a la dignidad; a continuación, c) proponemos una educación estética donde la belleza ligada al deporte no está exenta del sufrimiento, las limitaciones físicas o (...) psíquicas del individuo, para que seamos capaces de ver más allá de las formas, en orden a respetar y salvaguardar la dignidad de la persona humana; finalmente, d) reflexionamos sobre el concepto de belleza que profesores y entrenadores están trasmitiendo a los alumnos y a los deportistas a través del deporte, proponiendo un modelo en el que cabe el dolor, el sufrimiento, las limitaciones e imperfecciones sin dejar por ello de ser bellos.From theology and philosophy we can understand the concept of beauty in sport linked to human dignity. Therefore, in this article: a) we analyze, from the anthropology of Christianity, the body and the value of sport in the lives of human beings; b) we boarded the aesthetic trying to understand beauty linked to dignity; then c) we propose an aesthetic education where beauty linked to sport is not without suffering, physical or mental limitations of the individual, so that we are able to see beyond the forms, in order to respect and safeguard the dignity of the human person; finally, d) we reflect on the concept of beauty that teachers and coaches are transmitting to students and athletes through sport, proposing a model that fits the pain, suffering, limitations and imperfections while still being beautiful. (shrink)

Desde la certidumbre del sentido necesariamente inacabado, nómada y abierto de sus propuestas, el presente volumen de la Colección La Fuente da cuentas del esfuerzo de un grupo de investigadores del Instituto de Filosofía de La Habana (IF) y de la Universidad Autónoma de Puebla (BUAP) por esbozar, más que respuestas, aquellas interrogantes sociales, culturales y artísticas que, desde constelaciones cambiantes de conceptos y reflexiones estéticas, puedan ser emplazadas en sus respectivas realidades. El presente libro es el tercero de la (...) serie Redes, dedicada a plasmar los principales resultados del trabajo de colaboración del Cuerpo Académico de Estética y Arte de la BUAP con otros grupos de investigación. La coordinación de esta entrega contó con la sapiencia y laboriosidad académica de la doctora Alicia Pino Rodríguez (1954-2017), investigadora del IF, integrante del Consejo de la Colección, coordinadora de su segundo volumen y parte esencial de este, dedicado a su memoria. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Full Collection of Personal NarrativesGianna O'Leary, Paul Hostovsky, Yilu Ma, Leo Almazan, Hilda Sanchez-Herrera, Marisa Rueda Will, Elaine Hsieh, Manuel Patiño, Felicity Ratway, Liliana Crane, Laisson DeSouza, Nilsa Ricci, Linda Pollack-Jackson, Kelley Cooper, Mateo Rutherford-Rojas, Rosa C. Moreno, Maja Milkowska-Shibata, Patricia Coronado, and Catalina Meyer• A Day in the Life of a Spanish Interpreter• Deaf Interpreter• "Call me Dr. XXX!"• Translating Care for the Voiceless Patient• Are We There (...) Yet? A Narrative of Firsthand Interpreter Experiences in the Medical Field and Insights to Aid Language Access Compliance• One Interpreter's Journey of Interpreting for Pregnancy Loss• More Than Words: Communicating for the Quality of Care• From Linguistic Bridge Builder to Aspiring Physician• Towards Language Justice: A Call to Identify and Overcome Structural Barriers• Voices in the Shadows: The Hidden Complexities of Being a Medical Interpreter• The Voice of Patients: The Exclusive Work of a Human Who Can Advocate• Don't Mute the Messenger• The Ramp and the Stop Sign• How Policies and Practices in Medical Settings Impact Communication Access with Deaf Patients and Caregivers• And When May I Cry? Juggling Emotions in Healthcare Interpreting• To Engage or Not to Engage: An Interpreter and a Mother's Need for Connection in the Cardiothoracic Unit• Witnessing Trauma: Emotional Challenges in Medical Interpretation• Being an Interpreter—Beyond Linguistics• 1-800-Quit-NowCopyright © 2024 Johns Hopkins University Press... (shrink)

This article is part of a For-Discussion-Section of Methods of Information in Medicine about the paper "Biomedical Informatics: We Are What We Publish", written by Peter L. Elkin, Steven H. Brown, and Graham Wright. It is introduced by an editorial. This article contains the combined commentaries invited to independently comment on the Elkin et al. paper. In subsequent issues the discussion can continue through letters to the editor.

© The Author 2016. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved.Cell walls of grasses, including cereal crops and biofuel grasses, comprise the majority of plant biomass and intimately influence plant growth, development and physiology. However, the functions of many cell wall synthesis genes, and the relationships among and the functions of cell wall components remain obscure. To better understand the patterns of cell wall accumulation and identify genes that act in grass (...) cell wall biosynthesis, we characterized 30 samples from aerial organs of rice at 10 developmental time points, 3-100 d post-germination. Within these samples, we measured 15 cell wall chemical components, enzymatic digestibility and 18 cell wall polysaccharide epitopes/ligands. We also used quantitative reverse transcription-PCR to measure expression of 50 glycosyltransferases, 15 acyltransferases and eight phenylpropanoid genes, many of which had previously been identified as being highly expressed in rice. Most cell wall components vary significantly during development, and correlations among them support current understanding of cell walls. We identified 92 significant correlations between cell wall components and gene expression and establish nine strong hypotheses for genes that synthesize xylans, mixed linkage glucan and pectin components. This work provides an extensive analysis of cell wall composition throughout rice development, identifies genes likely to synthesize grass cell walls, and provides a framework for development of genetically improved grasses for use in lignocellulosic biofuel production and agriculture. (shrink)